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KMID : 0861020070220040279
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Korea Journal of Herbology
2007 Volume.22 No. 4 p.279 ~ p.286
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Effects of Cynanchum spp. on the hyperlipidemia in rats induced by Triton WR-1339
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Ham In-Hye
Lee Ju-Yeong
Yoon Ye-Jin
Yang Gab-Sik
Tae Jin
Bu Young-Min
Kim Ho-Cheol
Choi Ho-Young
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Abstract
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Objective : In order to compare of hyperlipidemia effect of C. wilfordii, C. auriculatum in korea and C. auriculatum in China, it was performed on the hyperlipidemia in rats induced by Triton WR-1339.
Method : The 70% MeOH extracts from dried root of C. wilfordii and C. auriculatum in korea and C. auriculatum in china were fractionated into H2O layer and CHCl3 layer. The level of total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol, AST and ALT in serum were used to observe the effectiveness of C. wilfordii korean C. auriculatum and chinese C. auriculatum.
Results : In the hyperlipidemic rats induced by Triton WR-1339, C. wilfordii and korean C. auriculatum significantly decreased total cholesterol, triglyceride, otherwise significantly increased HDL. And C. wilfordii and chinese C. auriculatum significantly decreased AST and ALT.
Conclusion : This study indicate that C. wilfordii korean C. auriculatum and chinese C. auriculatum were effective in the hyperlipidemic rats induced by Triton WR-1339. According to the results, C. wilfordii korean C. auriculatum and chinese C. auriculatum need to considered for the application in hyperlipidemia.
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KEYWORD
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Cynanchum wilfordii, Cynanchum auriculatum, hyperlipidemia, Triton WR-1339
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